Tesis durant el mes d'abril a la URL

Universitat Ramon LlullDues alumnes de la Universitat Ramon Llull han assolit el grau de doctor durant el mes d'abril. Laura Guillem Ramo i Meritxell Molist Fusté han llegit les seves respectives tesis amb la qualificació final de Excel·lent Cum Laude.

 

Laura Guillén Ramo (ESADE) A behavioral Approach to Emotional Intelligence: conceptual and measurement issues ha estat dirigida per Willem E. Saris i Richard Boyatzis:


The concept “emotional intelligence” (EI) resonates in the business world (Domagalski, 1999), and many authors have called for more research that clearly conceptualizes it (Sala, 2002; Becker, 2003, Day and Carroll, 2004). Within the controversy of defining EI, the behavioral approach, defining and measuring EI in terms of competences, has not received much attention.

This dissertation is based on data of three medium-sized Spanish organizations (n=223) that were involved in a competency management project based on emotional and social competencies as proposed by Goleman, Boyatzis and McKee (2002). The rationale of studying the appropriateness of the emotional competency model seems relevant and will serve to increase understanding of the field as a whole and prove its usefulness within organizational settings.

The starting point is a generic overview of the psychological and philosophical grounding of emotional intelligence. Then the scope of the analysis is reduced, step by step, to conclude with some concrete research proposals. These proposals are related to three major research areas within the field of EI that will mould the framework in which the empirical part of the dissertation will be inserted: the construct, discriminant and predictive validity of EI. Structural Modeling techniques available in the SEM program LISREL 8.51 software are used to enter the empirical analyses of the dissertation.

Results provide a comprehensive framework for the emotional and social competencies proposed by the EI model of Boyatzis and Goleman. The dissertation provides support to the idea of personality being something different from competencies as a proof of discriminant validity. Concerning the relationship between competencies and performance, predictive validity is confirmed empirically.

 

Meritxell Molist Fusté (IQS) Brassinoesteroides: síntesi d'anàlegs androstànics encaminats en aprofundir en la interacció brassinoesteroide-receptor ha estat dirgida per Carme Brosa Ballesteros:

Most of the efforts made nowadays in the field of brassinosteroids, plant growth promoting regulators, are focused on going in depth in the knowledge of the brassinosteroid-receptor interaction (where hydrogen bonding seems to play an important role) and on synthesizing analogs with good cost-activity ratio. In this way, it was considered interesting to study androstane brassinosteroid analogs.

In this phD thesis, some synthetic strategies have been developed to obtain androstane analogs with different side chains in a systematic and efficient way. Moreover, the 3D similarity between these analogs and some active brassinosteroids has been studied through flexible alignments using MOE program. The strategies developed to achieve A ring modifications have allowed -diol functionality introduction is mucha,3a2 us to observe how the -difluoro ora,3a2more easy and efficient than others such as  2,3-diketone.

Lots of trials to synthesize the most similar androstane analog to brassinolide have been made. Unfortunately, due to the synthetic difficulty to obtain 3S,4-dimethyl-2R-hydroxipentanoic acid (side chain) this analog synthesis has been unsuccessful.

A group of more than ten brassinosteroid androstane analogs have been designed, synthesized and bioactivity evaluated in order to study the influence of the hydrophobic side chain region, the polar functionality position and the role of some protective groups.

With the aim to validate the SHOP methodology, previously applied in our team, some androstane analogs with commercially available side chain have been obtained and bioactivity evaluated. The synthesis and activity evaluation of some analogs with different 2’-functionalities (fluorine, azide, amine...) and of those selected by molecular modeling techniques (SHOP methodology) have let conclude that a hydrogen bond donor group.

 

+ info: Tesis Doctorals en Xarxa